Innovations

HIV/AIDS continues to disproportionately impact sub-Saharan Africa, where it remains a leading cause of illness and death among children. Paediatric HIV progresses at an alarming rate, with 20–30% of untreated infants succumbing to the disease within their first year. Without timely intervention

The CSIR has established a bioconversion platform that focuses on alternative pathways for chemical production. The platform is geared towards local production and replacing imports of bio-based platform chemicals, including lactic acid. This shift will have a direct impact on the bioeconomy. The

The current patterns of production and consumption of conventional plastics are unsustainable. Conventional plastics are non-biodegradable, leading to visible pollution in soil, marine environments and the air when discarded, landfilled or burnt. Products that are practically non-recyclable, such as

This invention relates to a single-cell assay designed to determine how chromosomal contacts influence the transcriptional activity of genes of interest. It also includes methods for silencing gene expression by disrupting gene regulatory elements involved in these chromosomal interactions.

The present invention relates to methods for modulating the production of ELR+ proinflammatory chemokines in a subject or a cell using either UMLiLO IncRNA inhibitors to decrease production of ELR+ proinflammatory cytokines or using UMLILO IncRNA to increase the production of ELR+ proinflammatory

The present invention relates to methods for the identification of anti-HIV miRNAs and anti-HIV pharmaceutical compounds using high-throughput screening methods, comprising: transfecting reporter cells with a panel of miRNAs, infecting the reporter cells with HIV, screening the cells to identify

The present invention relates to methods and compositions for modulating the control of apoptosis, specifically for modulating the interaction between hnRNP-K and lincRNA-p21 to induce or prevent apoptosis in the cell.

This technology offers a next-generation creatine powder formulated with food-grade components that enable instant mixing in water and long-term shelf stability. When added to liquid, the powder disperses rapidly and forms a clear, grit-free solution within seconds, avoiding the sedimentation and

This product contains beneficial microbes found in fruits and vegetables. When applied to crops, these microbes naturally improve growth, nutrient use, and crop quality. When produce is consumed raw, it also helps support digestion and gut health. It is especially well-suited for ready-to-eat fruits

We have developed a method to clinically measure and predict chronic stress and stroke risk by interpreting three blood test results and a blood pressure reading in a specific relation to one another. Applications / Relevant Industries A timeous, accurate prediction of stress and stroke risk

Fleet owners and distribution agents face a myriad of challenges. These include crimes such as cargo theft and hijackings; vehicle misuse; and high costs of fuel, insurance and maintenance, including mechanical failures and power outages affecting traffic flow. The CSIR has developed a web-based

Acute kidney injury presents as a rapid decrease in renal function and can be caused by severe trauma, illness, surgery or chronic medication, such as the use of antiretroviral treatment. Many assays used in disease detection were developed decades ago, and their performance is lacking. This is the