New Frontier in Precision Diagnostics for Long COVID and Inflammation

This technology introduces a diagnostic method and kit that detects inflammatory diseases by measuring fibrin amyloid microclots (FAM) and Neutrophil Extracellular Traps (NETs) found in patient blood. These two components often bind together to form microclot-associated NETs (MiNETs), which are significantly elevated in patients with conditions such as Long COVID, rheumatoid arthritis, cancer, diabetes, IBS, and acute infections.

The method uses fluorescent staining, imaging technologies, and machine-learning analysis to identify and quantify these MiNETs from a small blood sample. The kit includes dyes that bind to fibrin amyloid microclots as well as fluorescent markers for NET components.
By enabling accurate measurement of MiNETs, the technology supports earlier diagnosis, better disease monitoring, and improved patient stratification for treatment in inflammatory and immune-related conditions.