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Acute kidney injury presents as a rapid decrease in renal function and can be caused by severe trauma, illness, surgery or chronic medication, such as the use of antiretroviral treatment. Many assays used in disease detection were developed decades ago, and their performance is lacking. This is the
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Drug regimens have not been optimised for individuals of African descent. This is due to several converging factors, including Africa’s diverse genetics, disproportionate disease burdens (and consequently a high dependency on specific drug regimens), as well as under-representation of local
This technology relates to the transdermal treatment of diabetes. In particular, to a formulation for the transdermal delivery of the photoactive antidiabetic agent diosgenin that is encapsulated and protected by an oil-in-water nanoemulsion matrix for the treatment of type 11 diabetes Mellitus
The innovation is the rational combination of ezetimibe and curcumin for the treatment of colon cancer- which means one can apply a cancer therapeutic, orally. This would have significant value to the African population and solve key issues like the packaging and distribution of chemotherapeutic

This invention is an electronic medical, digital device that computes and grades the stages of Asthma aetiology and severity using wearable biosensors and environmental Nanosensors, with the capacity to predict imminent Asthma attacks and future attacks. The Asthma grid uses an algorithm to compute

This invention is continuous flow reactor technology used to manufacture active pharmaceutical ingredients (APIs) for various drugs. These include AIDS ( Emtricitabine, Lamivudine and Efavirenz), TB (Isoniazid), influenza (Tamiflu) and diabetes (Gliclazide, chlorpropamide, glipizide, glibenclamide

The need for accurate, rapid and sensitive detection of bio-molecules is becoming ever more pressing. The aforementioned are needed in several industries, ranging from clinical diagnostics and screening to assessing microbial contamination in water and even plant disease diagnostics, to name just a

A scalable pneumatic cushion features an array of pressure-controlled air cells, each equipped with a pressure sensor for closed-loop control. This allows for precise regulation of pressure in high-risk areas, promoting blood flow and reducing localized pressure. The system uses a microcontroller to
The PAGA is an all-in-one anthropometric device designed for preterm and fragile infants, providing accurate, minimally invasive growth measurements in hospital and clinic settings, including low-resource environments. It captures all key metrics in one tool: weight, length, head circumference, foot
This technology introduces a new class of zwitterionic polymers designed to gently break apart lipid bilayers and form stable lipid nanodiscs. These nanodiscs can capture and isolate membrane proteins in an environment that closely mimics their natural state. At the core of the invention is a
ImmerseCell is a virtual reality experience (VLE) to teach undergraduate and postgraduate students about key cellular structures with an interactive, narrated, guided experience (Figure 1, Figure 2). The team utilised real-world microscopy data of various key cellular structures in the mammalian
Researchers at Stellenbosch University have developed a proprietary buffer that enables a high-temperature (50°C) IVT process, solving a key industry challenge. Unlike standard buffers that suffer a ~40% yield loss at high temperature, this formulation maintains ~93% RNA yield with standard enzyme