Innovations

The toTIL Score is an innovative scoring system designed to predict the likelihood of cancer patients responding to immunotherapy based on the level of tumour-infiltrating lymphocytes (TILs) within the tumour. By evaluating the extent and distribution of TIL infiltration, the toTIL Score provides a

Plasmid DNA-based Rescue of Orbiviruses (African Horse Sickness) refers to a reverse genetics approach that enables scientists to generate infectious orbiviruses entirely from cloned DNA. In this system, the segmented RNA genome of the African horse sickness virus (AHSV), a member of the Reoviridae

The Motswadi System is a SIM-card–based technology designed to support parents in protecting their children from cyberbullying and sexting. The SIM card is linked to a mobile application that enables parents to monitor and manage their child’s online activity across mobile phones, tablets, and

Keloid disease represents a significant and growing unmet need in dermatology and surgical care. The disease is characterised by abnormal scar formation that extends beyond the original wound site. Despite the availability of treatments such as surgery, corticosteroid injections, radiotherapy, and

This innovation is a first-in-class antidepressant designed to improve mood, cognitive function, and appetite regulation. Preclinical studies have demonstrated antidepressant effects comparable to existing therapies, with additional benefits for cognition, motivation, and appetite balance. The

Climate-Smart Drought-Resistant Agriculture Platform This innovation is a sustainable farming enterprise that combines drought-resistant crops and vegetables, efficient water management, and climate-smart farming techniques to ensure year-round food production despite changing weather patterns and

Keloid disease is a chronic fibroproliferative skin disorder characterised by excessive scar tissue formation that extends beyond the boundaries of the original wound. Accurate diagnosis remains challenging due to the heterogeneous nature of keloids and their similarity to other fibroproliferative

Overview of the Innovation: Drought-Resistant Crops and Vegetables in Eswatini The innovation involves the cultivation and promotion of drought-resistant crops and vegetables using climate-smart agricultural practices to address the challenges of recurring droughts, water scarcity, and food

Thakadu Energy™ is an innovative South African energy technology developed by Thakadu Holdings and Investments (Pty) Ltd. The innovation aims to provide affordable, AI-powered backup energy solutions for households, businesses and communities experiencing unreliable electricity supply or lacking

Dalr is a direct-to-fan digital commerce platform developed by CreativeShield to help African creators sell digital products, music, exclusive content, merchandise, tickets, and future premium services directly to their audiences. The platform gives creators a simple online commerce layer where they

Our innovation introduces a centralized, digitally managed civil construction equipment and plant hire logistics model in Refengkgotso. Local township contractors and micro-enterprises are systematically excluded from executing major public sector tenders because they lack affordable access to heavy

The ZacMulti-Kiosk™ Mobile Express is an all-in-one, self-service digital services hub brought to market by Zac-Mokoena Trading and Investment. It consolidates multiple premium capabilities—including document services (printing, copying, and high-speed A4/legal scanning), digital identity