The present invention relates to methods for the identification of anti-HIV miRNAs and anti-HIV pharmaceutical compounds using high-throughput screening methods, comprising: transfecting reporter cells with a panel of miRNAs, infecting the reporter cells with HIV, screening the cells to identify...

The present invention relates to methods for modulating the production of ELR+ proinflammatory chemokines in a subject or a cell using either UMLiLO IncRNA inhibitors to decrease production of ELR+ proinflammatory cytokines or using UMLILO IncRNA to increase the production of ELR+ proinflammatory...

This invention relates to a single-cell assay designed to determine how chromosomal contacts influence the transcriptional activity of genes of interest. It also includes methods for silencing gene expression by disrupting gene regulatory elements involved in these chromosomal interactions.

The CSIR has developed the next-generation ground-based surveillance and classification radar that enables automated detection and classification of movement over a wide area, enabling proactive protection of wildlife and other security applications.

With the insights gained from Meerkat 1, the CSIR...

Radar technology is well suited to solutions such as those to protect helicopters. The CSIR was approached by SAAB Grintek Defence, a leading supplier of aircraft self-protection suites, to collaboratively develop a radar-based hostile fire indicator sensor to add to its existing platform protection...

A camera, roughly the size of that used for CCTV, can locate gunshots by detecting potassium emissions from the muzzle flash. Dubbed, ‘The K-line camera’ (K being the symbol for potassium on the periodic table), it can be integrated into a CCTV network in a hotspot area for gun-related crime...

The CSIR has developed a smartphone technology that is used as a detection system for analysing biomolecular assays or chemical reactions. The smartphone is used to capture one or more images of the biomolecular assays, which are processed by way of bespoke hardware and software to provide...

Some 13,000 ships enter South Africa’s eight ports annually. These ports process some 10,000 containerised loads per day. Many industries rely on imports and exports via the country’s ports, where a safe port environment, with minimal disruptions while loading or offloading cargo, is critical...

Monoclonal antibodies (mAbs) are immune system proteins that are used in targeted drug therapy and prophylaxis and are in high demand around the world to fight diseases. Despite advancements in biomedical technology, current methods for producing mAbs – primarily mammalian cell cultures – can be...

Fleet owners and distribution agents face a myriad of challenges. These include crimes such as cargo theft and hijackings; vehicle misuse; and high costs of fuel, insurance and maintenance, including mechanical failures and power outages affecting traffic flow. The CSIR has developed a web-based...