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Clinical effectiveness of lopinavir in the management of Covid-19 infection and prevention.

COVID-19 also known as Coronavirus 2019, is currently declared by WHO as a new pandemic
disease caused by a single-stranded RNA zoonotic virus termed severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) (Lu et al. 2020). The complete viral genome analysis shows that the
virus shares 88% sequence identity to two bat-derived severe acute respiratory syndrome (SARS)-
like coronaviruses, but more distant from severe acute respiratory syndrome coronavirus (SARSCoV) (Lu et al. 2020). Coronavirus is an enveloped and single-stranded ribonucleic acid named
for its solar corona like appearance

Magnetic beads nucleic acid extraction technology

The bottleneck to most of the molecular (PCR) testing is due to lack of nucleic acid extraction kits. Where available, the possibility of automation enhances the speed with which one can access high throughput extraction. Therefore, development and manufacture of efficient extraction reagents is the first step towards pandemic/infectious disease outbreak readiness. The lessons from Covid-19 outbreak should include countries readying themselves against such outbreaks by manufacturing their own reagents and having the ability to ramp up production when necessary. Our product development and

Cacadu Development Agency

Cacadu Development Agency is an entity of the Sarah Baartman District Municipality whose mandate is to spearhead catalytic economic development in the District across a variety of industrial sectors by engaging with relevant investors and stakeholders. These industrial sectors include:

1. Agriculture and Agro-processing;

2. Tourism;

3. Manufacturing;

4. 4IR;

5. Renewable Energy;

6. Township Industry Development

Quarantuning at the time of Coronavirus

This research project looks at how Quarantine was used as a preventative measure in the fight against Covid-19. It seeks to asses the impact of Quarantine towards flattening the curve. It also delves deeper into the concept of Quarantine and how South Africans got to experience it and apply it in their daily lives between March 2020 and July 2020 as social distancing became a health imperative.

Resection

We are a female-owned startup working on developing a manufacturing plant, that manufactures asphalt using plastic waste to substitute some of the bitumen currently used.

Identification of potential SARS-CoV-2 inhibitors from South African medicinal plant

-Our team identified compounds found in South African indigenous plants that would target SARS-CoV-2 using molecular docking
-We want to now take this further and commence In vitro studies as well as in vivo rat models

Hope Medical and Engineering Suppliers

Hope Medical and Engineering Suppliers specialise in the supply of medical and engineering consumables and equipment.

Akili Labs

Akili Labs is an award-winning biotechnology company specialising in molecular diagnostic systems development, founded by Charles Faul and Lucas Lotter in 2017, with Dr Farhan Pervaiz joining as a co-founder in 2018.

Based in South Africa with international affiliates, Akili Labs was established after realising the need for easy access to fast-paced diagnostics in the healthcare system.

With innovation and collaboration at the forefront of its company purpose, Akili Labs constantly forges partnerships with organisations around the globe for the development, creation and implementation of

Sibaz Empire 1606

Sibaz Empire 1606 is a black 100% female-owned business, owned entirely by Nokuthula Masiba. The company is a waste management company that intends to create innovation in waste collection and recycling. As our business is based on collecting waste using smart technology, our inventory storage will be located in multiple places in the Western Cape. Startup requirements will be financed through government grant funding and equity partnership.

DETECTION AND MONITORING OF SARS-CoV-2 RNA FRAGMENTS IN WASTEWATER USING A MALDI-TOF MASS SPECTROMETER

The purpose of this study is to develop an analytical test method for the detection and quantification of SARS-CoV-2 RNA fragments in sewer wastewater, using a MALDI-TOF mass spectrometer. With this technology, we intend to obtain test results within a few minutes, thus enabling us to confirm the presence or absence of SARS-CoV-2 and measure viral load in the water. Introducing this technology will facilitate rapid detection and mapping of the Covid-19 epidemic in communities, which can aid authorities to implement strategies to prevent its spread swiftly. The developed analytical test method

Think2099

Think2099 is a human-centered strategy and innovation consultancy helping our clients re-think business, people and planet in a social responsible, environmentally sustainable way.

Think2099 was born from an intolerant dissatisfaction with the status quo. Our team believes in the fundamental concepts of shared value and maximum impact. The only way to get there is by combining multiple perspectives, a passion for people, analytical rigour, and deep industry knowledge. We transform insights into impactful, human-centered solutions.

Nelson Mandela Bay iHub

The Nelson Mandela Bay iHub is a business incubator located in Port Elizabeth that supports businesses in ICT. The iHub has a specific focus on technologies that have the potential to disrupt existing value chains and facilitate market access for our incubatees whilst contributing to social development. Our sectors of interest include (but not limited to) educational technology, smart agriculture, automation and robotics, big data analytics, cloud computing and blockchain technology.

The main service offerings of the iHub are:

Business Development - The centre offers business development

ICT Intelligence (Pty) Ltd

ICT Intelligence specializes in the full end to end data and information life cycle with solutions that cater to Data Ingestion, Data Profiling, Data Storage (Big Data, DW), Data Visualizations, Cognitive/Robotic Process Automation, Data Visualization, AI/Machine Learning, Blockchain and data security and compliance. We provide all these services and solutions in multiple ways, on-prem, in the cloud or as a service. We have done Strategies, Road Maps, Blue Prints, and Implementation of the above solutions across Banking, Insurance, Telco’s, Manufacturing, Retail, and for COVID19 to name a few

Sebenza Waste Solutions

At Sebenza Waste Solutions, we aspire to be more than just a smart waste collector company. Our vision is to develop a sustainable recycling solution for designated materials that is a model of excellence, environmentally responsible, and economically viable. To provide our customers with an exceptional solution with disposal products and protect, preserve and improve our environment and the quality of life in the communities we serve. Sebenza Waste Solutions Business goal is to enhance and grow its core smart waste-collecting business widely in the Western Cape with the intent to grow

A COVID-19 detection home kit

The research involves developing a simple home detection kit for COVID-19. The first stage of the project involves the identification of proteins from bacteria that has a binding affinity to specific sites on the SARS-CoV2 S protein. Computational analysis will investigate the binding potential of the antiviral cyanobacterial proteins including cyanovirin-N, scytovirin and phycocyanin with the fundamental proteins involved in attachment and replication of SARS-CoV-2. Following the computational analysis, the second stage will require building the molecular detection using specific bacterial

Lived experiences of emergency care personnel in the Western Cape, South Africa during the COVID-19 pandemic: a longitudinal hermeneutic phenomenological study

The purpose of this study was to understand the lived experiences of emergency care personnel in the Western Cape. The study followed a longitudinal hermeneutic phenomenological approach, using one-on-one interviews to collect data. Data were analysed using Ricoeur's approach.