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Gwork is a developer of online people management platform designed to measure employee performance and drive accountability in remote teams. The company's platform uses behavioural and organizational psychology principles infused with gamification to provide data-driven insights on patterns, trends and gaps in employee productivity, enabling businesses to shape remote team culture for team alignment, enhanced employee engagement and improved performance from employees.

Sector
ICT
Type of Investees
Startups
Provinces
Western Cape
Direct Investments
Anza Capital
Business Model
B2B
Company Life Stage
Pre-revenue
Website link
https://gwork.io/

Hair Town is a leading South African online retailer specialising in high-quality wigs, bundles, and hair extensions, especially Brazilian, Peruvian, and Vietnamese hair. Their wide range includes beginner-friendly and premium collections, lace frontals & closures, ponytails, and stylish wigs by cap type. They complement their product offerings with after-care essentials, accessories, and tools. With over 7,500 customer reviews, loyalty rewards, flexible payment options (“Buy Now, Pay Later”), and frequent sales and collections, Hair Town focuses on quality, style, and a seamless customer experience.

Sector
Small business
Implementing Partners
SA SME Fund
Type of Investees
Startups
Provinces
Gauteng
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://www.haircity.co.za/

HYENA is a spin-out company from the Department of
Chemical Engineering at the University of Cape Town. HYENA has developed the POWER POD as a solution to deploy fuel cell technology into Africa, where hydrogen distribution is all but non-existent. HYENA’s POWER POD is a diesel generator replacement technology that produces on-site, on-demand and reliable electricity.

Sector
Energy
Implementing Partners
TIA
Type of Investees
Startups
Provinces
Western Cape
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://www.hyena.com/

Hypernova Space is a technology company that develops innovative space hardware & provides thermal vacuum test services for the aerospace industry.

Sector
Mining
Implementing Partners
SA SME Fund
Type of Investees
Startups
Provinces
Western Cape
Business Model
B2B
Company Life Stage
Pre-revenue

Hyrax Biosciences is an award-winning genetic software company that takes the complexity out of sequence data analysis for companies around the world. Its automated platform, Exatype, a leading bioinformatics software platform, combines scalable tech and unique algorithms to deliver detailed and accurate genotype reports, without the need for human intervention or the threat of human error.

Sector
Health
Implementing Partners
SA SME Fund
TIA
Type of Investees
Startups
Provinces
Western Cape
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://hyraxbio.com/

I-G3N is a lithium battery manufacturer – leading in the South African market. I-G3N is an innovative company that focuses on clean energy solutions. It provides high-quality energy storage units, which can be used in homes, offices, and electric cars. It also strives to provide affordable, sustainable, and renewable energy solutions to African homes and businesses. I-G3N is a dynamic group of individuals that are dedicated to developing clean-energy solutions for South Africa, Africa, and the world. 

Sector
Manufacturing
Implementing Partners
SA SME Fund
Type of Investees
Startups
Provinces
Gauteng
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://www.i-g3n.co.za/

Immobazyme is a South African biotechnology spin-out company of Stellenbosch University that utilises precision fermentation to produce high-value active protein ingredients. Their mission is to catalyse the future of global innovation with precision fermentation. By creating the most desirable and accessible recombinant proteins, they aim to enable businesses to perfect their products and unlock the full potential of their process development.

Sector
Health
Implementing Partners
TIA
Type of Investees
Startups
Provinces
Western Cape
Direct Investments
Anza Capital
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://www.immobazyme.com/

Impulse Biomed is a developer of medical devices dedicated to making healthcare more affordable. One such product is the Easy Squeezy, an asthma pump device that makes it easier for people to activate their inhalers. Another product is ZiBiPen, adrenaline auto-injectors can be customized for any patient, such as the needle length, dose, and more, enabling patients to get an emergency treatment of anaphylaxis.

Sector
Health
Implementing Partners
TIA
Type of Investees
Startups
Provinces
Western Cape
Direct Investments
Anza Capital
Business Model
B2B
Company Life Stage
Pre-revenue
Website link
https://www.impulsebiomed.com/

INSiAVA is a spinout from the University of Pretoria that specializes in the design and development of the world's most advanced integrated circuits for digital passive infrared smart sensors

Sector
ICT
Manufacturing
Implementing Partners
TIA
Type of Investees
Startups
Provinces
Western Cape
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://www.insiava.com/

iThemba Laboratories for Accelerator Based Science (LABS) is a business unit of the National Research Foundation (NRF) and committed to invest in the growth and development of scientific and technical competence in the field of accelerator-based science, with a special focus on women and designated communities. iThemba LABS has implemented the following projects:
- iThemba LABS developed an Anti-cancer Radiopharmaceutical Theranostic, a novel conjugated molecule targeting the inhibition of metalloprotease (ADAM10) s a cell-surface-expressed metalloproteinase. It is a type of protein enzyme with a catalytic mechanism involving a metal.
- Ion Beam Writing
- PANGoLINS : Portable African Neutron-Gamma Laboratory for Innovative Nuclear Science project aimed at furthering investigation measurements of neutrons which forms an important component part on site or in transit and the detection of both fissile material for the use in decarbonised energy sources or disposal thereof.

Sector
Health
Implementing Partners
TIA
Type of Investees
Strategic Innovation Projects
Provinces
Western Cape
Business Model
Licensing
Company Life Stage
Pre-revenue
Website link
https://tlabs.ac.za/

Kasha is Africa’s leading digital health platform, combining e-commerce, last-mile delivery, and AI-driven insights to make quality health and wellness products accessible across the continent. With a strong focus on women’s needs, Kasha empowers individuals by offering trusted products, clear information, and the freedom to choose what best fits their lives, while ensuring reliable delivery even in hard-to-reach areas.

Sector
ICT
Transportation
Implementing Partners
SA SME Fund
Type of Investees
Startups
Provinces
Western Cape
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://kasha.co/

Apply for Funding from the CMT Research Foundation

Overview of your opportunity

The CMT Research Foundation is committed to delivering treatments and cures for Charcot-Marie-Tooth disease (CMT) through targeted funding for high-potential scientific research. Grants support research leading to the development of therapeutics for all CMT types, based on the foundation’s research priorities, though innovative new approaches are also welcomed.

Closing date
Monday, November 17, 2025 - 12:00
Read more

Kena Health is an app-based telemedicine solution in South Africa which has, to date, facilitated more than 20,000 consultations. With the Kena Health™ App, you can talk directly to a nurse, doctor or mental health professional using text, voice, or video. The app is currently available on both the Android (Google) and Apple app stores. It is a value-based care telemedicine offering which allows patients to speak to doctors, nurses, and mental health professionals in an app-based interface.

Sector
Health
ICT
Implementing Partners
SA SME Fund
Type of Investees
Startups
Provinces
Gauteng
Direct Investments
27Four
Business Model
B2C
Company Life Stage
Post-revenue
Website link
https://web.kena.health/

The Kirontech Platform empowers health insurers with focused solutions for payment integrity, data integrity and readiness, and health outcomes and quality. Intuitive, comprehensive, accurate Fraud, Waste, and Abuse detection, investigation and Health Outcomes Management.

Sector
Health
Implementing Partners
SA SME Fund
Type of Investees
Startups
Business Model
B2B
Company Life Stage
Post-revenue
Website link
https://kirontech.com/

Koa Academy is an online school in South Africa, offering a comprehensive education experience that combines the best elements of modern learning. This fully online pod school caters to students from grades 4 to 12, delivering education that is both individualised and robust.

Sector
ICT
Type of Investees
Startups
Provinces
Western Cape
Direct Investments
Anza Capital
Business Model
B2C
Company Life Stage
Post-revenue
Website link
https://koaacademy.com/

In a world of rising customer expectations, reputable brands perpetually see the need to move at the speed of technology to catch up. Therefore, KTO Digital was launched to offer unfathomable expertise across the entire customer journey, including technology, digital commerce, IT consultancy, ERP/CRM, UX/UI, data aggregation, brand production, and communication to offer end-to-end solutions that deliver trailblazing innovation.

Sector
ICT
Implementing Partners
TIA
Type of Investees
Startups
Provinces
Gauteng
Business Model
B2C
Company Life Stage
Post-revenue
Website link
https://www.kto.co.za/

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