This global Grand Challenge seeks to fund breakthrough innovations that significantly reduce the cost of diagnostic and screening tools for use in low- and middle-income countries (LMICs). The focus is on developing scalable, high-impact technologies that can deliver diagnostic results at approximately USD 1 per test or near-zero incremental cost, while maintaining quality, speed, and usability in low-resource settings. 

This global Grand Challenges call for proposals seeks to accelerate the development of innovative interventions targeting placental and maternal gut inflammation and oxidative stress to improve fetal growth outcomes.

Fetal Growth Restriction (FGR) remains a major contributor to neonatal mortality and long-term health complications, particularly in low- and middle-income countries. This call aims to support scalable, science-driven solutions that can generate decision-grade evidence and advance toward clinical application.

The Grand Challenges initiative has launched a global call for proposals seeking breakthrough innovations that can significantly reduce the cost of treating Severe Acute Malnutrition (SAM) while maintaining or improving treatment outcomes.

The Alliance for Health Policy and Systems Research is inviting proposals for applied policy and political economy research to accelerate the implementation and expansion of health taxes.

This call aims to fund up to three country teams to conduct real-time policy analysis and strategy co-production that directly supports national-level health tax reform. The focus is not academic theory alone, but actionable insights embedded within ongoing national policy processes.

The iLCT Pipeline Research Acceleration Programme is a targeted funding call launched by Cure Parkinson’s to accelerate high-priority therapeutic candidates toward clinical trials for Parkinson’s disease.

This programme forms part of the International Linked Clinical Trials (iLCT) initiative, a global drug selection and evaluation platform established in collaboration with the Van Andel Institute. The iLCT committee comprising over 20 world-leading Parkinson’s experts annually reviews and ranks candidate compounds with disease-modifying potential.

The Nkulo Community Partnership Trust has issued a Call for Proposals inviting impactful, community-centred projects that create sustainable social and economic value in communities connected to Thungela operations and designated labour-sending areas.

The Trust seeks to partner with organisations delivering measurable, long-term outcomes in areas that strengthen local resilience, economic participation and community wellbeing.

This call prioritises initiatives that: