Southern Africa Innovation Support Programme (SAIS) 2 is a regional initiative that supports the growth of new businesses through strengthening innovation ecosystems and the promotion of cross-border collaboration between innovation role-players in Southern Africa. The Programme focuses on strengthening early-stage enterprises and young entrepreneurs, connecting innovation ecosystems, and promoting innovations serving socially or economically disadvantaged populations. The overall objective of SAIS 2 is enhanced regional innovation cooperation and national innovation systems contributing to