Licensing

The invention relates to methods for producing gold nanoparticles functionalised with a telomerase substrate, or a linker nucleic acid having a region complementary to a nucleic acid comprising a telomerase substrate, for use in detecting telomerase activity. Functionalised gold nanoparticle...

The invention relates to compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions, particularly wherein said telomere related diseases and/or telomere related medical conditions are cancer and cellular ageing. Particularly, herein is disclosed 37 kDa...

The Council for Scientific and Industrial Research (CSIR) has rigorously investigated and conducted preclinical studies on the use of the South African indigenous plant species, Siphonochilus aethiopicus, commonly known as African ginger, in the treatment of allergic and respiratory diseases...

The Council for Scientific and Industrial Research (CSIR), in collaboration with its partners, has successfully developed an advanced biomanufacturing process for producing Recombinant Human Insulin. The technology involves microbial fermentation and purification of bulk drug substance, ensuring...

The innovation describes a process for removing lead from a liquid such as contaminated water. The liquid is brought into contact with a PbrD protein which binds lead ions present in the liquid. The bound lead ions can then be recovered, for example as an insoluble salt or compound such as lead...

The present invention relates to methods and compositions for modulating the control of apoptosis, specifically for modulating the interaction between hnRNP-K and lincRNA-p21 to induce or prevent apoptosis in the cell.

The present invention relates to methods for the identification of anti-HIV miRNAs and anti-HIV pharmaceutical compounds using high-throughput screening methods, comprising: transfecting reporter cells with a panel of miRNAs, infecting the reporter cells with HIV, screening the cells to identify...

The present invention relates to methods for modulating the production of ELR+ proinflammatory chemokines in a subject or a cell using either UMLiLO IncRNA inhibitors to decrease production of ELR+ proinflammatory cytokines or using UMLILO IncRNA to increase the production of ELR+ proinflammatory...

This invention relates to a single-cell assay designed to determine how chromosomal contacts influence the transcriptional activity of genes of interest. It also includes methods for silencing gene expression by disrupting gene regulatory elements involved in these chromosomal interactions.

Developed at North-West University by Prof Erica Derbyshire following a major study, the toolkit is a structured, nine-chapter workbook designed to build essential financial skills for small business owners. It covers topics such as financial planning, bookkeeping, taxation, investment decisions...