Innovations

This invention relates to a single-cell assay designed to determine how chromosomal contacts influence the transcriptional activity of genes of interest. It also includes methods for silencing gene expression by disrupting gene regulatory elements involved in these chromosomal interactions.

The present invention relates to methods for modulating the production of ELR+ proinflammatory chemokines in a subject or a cell using either UMLiLO IncRNA inhibitors to decrease production of ELR+ proinflammatory cytokines or using UMLILO IncRNA to increase the production of ELR+ proinflammatory

The present invention relates to methods for the identification of anti-HIV miRNAs and anti-HIV pharmaceutical compounds using high-throughput screening methods, comprising: transfecting reporter cells with a panel of miRNAs, infecting the reporter cells with HIV, screening the cells to identify

The present invention relates to methods and compositions for modulating the control of apoptosis, specifically for modulating the interaction between hnRNP-K and lincRNA-p21 to induce or prevent apoptosis in the cell.

Monoclonal antibodies (mAbs) are immune system proteins that are used in targeted drug therapy and prophylaxis and are in high demand around the world to fight diseases. Despite advancements in biomedical technology, current methods for producing mAbs – primarily mammalian cell cultures – can be

SThis technology is to recover beer that would have been discarded, it is effective and can easily be incorporated into current brewing technologies as a way of reducing waste and increasing profit. By separating the beer from the spent yeast, and treating it with ultraviolet (instead of heat

The technology relates to an improved method for reclaiming waste beer from a brewing process. The process ensures the sterilization and re-use of beer that would otherwise be lost in the brewing process due to contamination. The method focuses on recovering beer lost in the fermentation stage

The invention relates to a method of fabricating a commercially viable biodegradable and transparent resistive random-access memory (ReRAM) chip with substantially high (>7 orders of magnitude) resistive switching behaviour using low operating power. The method makes use of a simple and affordable

The invention relates to an automated process for fabricating nano and micro structures using high temperature superconducting quantum interference device (SQUIDS). This method overcomes the high cost and complexity in the manufacturing process of superconductors for a commercial scale or mass

The High Agility Hybrid Serial-Parallel Kinematic Robotic Arm architecture leverages the benefits of serial and parallel kinematic machines while minimising the disadvantages of each. The design is based on the transmission of mechanical power via embedded drivetrains to each joint in the system

With our society facing challenges related to sustainability i.e. resource depletion and waste accumulation, the future success of the chemical and polymer industries relies on the use of renewable feedstocks. Lignin, one of the main components of non-edible lignocellulosic biomass shows great